Diagnosis Treatment & Management of Ankylosing Spondylitis
Spasms in spinal muscles in AS patients cause pain and limitation of motion.
The addition of a muscle relaxant to a NSAID helps decrease muscle pain and tightness.
The most common side effect of muscle relaxants is sleepiness.
Taking the medicine early in the evening can minimize the possibility of tiredness.
Disease-Modifying Agents (DMARDs)
DMARDs are drugs that work more slowly than NSAIDs but have the capability of modifying the progression of disease.
These drugs have greater benefit in rheumatoid arthritis.
DMARDs do not have a beneficial effect on spinal disease.
Some benefit may exist for arthritis of peripheral joints like the shoulders and hips.
Examples of DMARDs include sulfasalazine, methotrexate, and leflunomide.